​THE ENDOCANNABINOID SYSTEM (ECS)

We suggest watching this recent TedTalk done by Ruth Ross
While the end of the TedTalk focuses on the effects of THC and how our cannabinoid receptors work.  Below are some common facts that we may not all know:
  • Present in all humans, we have the endocannabinoid system to respond to our environment and effects our emotional responses. 
  • Receptors are present throughout the body including in our -brains, digestive system, and lymphatic system.
  • Our endocannabinoid system is crucial in childhood development and assist in the brain forming synapses. 
  • We have two different receptors for endocannabinoids which are  CB1 & CB2 
The endocannabinoid system (ECS) regulates levels of the endocannabinods throughout our body depending on different stimilus from our environments. 

​MECHANISMS OF ACTION

Anandamide was first described in 1992 by Raphael Mechoulam and his lab members W. A. Devane and Lumír Hanuš.
Cannabidiol (CBD) binds to a G-coupled protein, TRPV-1, which influences inflammation, pain perception and body temperature.  For a more in depth read we suggest reading through the following articles.

Research Paper: Signaling and Function in the Central Nervous System
"Various cannabinoids have diverse effects on the receptors, functioning as agonists, antagonists or partial antagonists, as well as affecting the vanilloid receptor. Many known effects of cannabis can be explained on the basis of this mechanism of action as can the use of cannabis in various conditions including multiple sclerosis, Parkinson's disease, glaucoma, nausea, vomiting and rheumatoid arthritis." [Ned Tijdschr Geneeskd. 2006 Jan 21, The mechanism of action of cannabis and cannabinoids]

Memory Formation

Within our hippocampus we have a large amount of endocannabinoids and receptors.  These assist with the formation of helpful memories. Similar to the memories when we retrieve dates, lists, or when we need to remember multiple items. 

*WARNING PLEASE READ BELOW*

This information is presented for educational purposes only. BathBombsPetersburg compiled this information to provide an understanding of the potential applications of cannabinoids. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.